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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 679250Generated: October 30, 2026

Hydrochloric Acid → 3-{1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl}-N-(4,5-dichlorothiophene-2-sulfonyl)prop-2-enamide

https://huagongshe.com/reaction/679250

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
ReactantDichloromethaneHCID 6344—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant1-HydroxybenzotriazoleHCID 75771—
ReactantDiisopropylethylamineHCID 81531—
Reactant4,5-Dichlorothiophene-2-sulfonamideHCID 3722094—
ReactantHCID 66917827HCID 66917827—
Product3-{1-[(2,4-Dichlorophenyl)methyl]-5-fluoro-3-methyl-1H-indol-7-yl}-N-(4,5-dichlorothiophene-2-sulfonyl)prop-2-enamideHCID 57354844—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-30a270084d8a4a4f800632b27c780dca
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)