HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Milrinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-(Ethoxymethylene)propanedinitrile | HCID 67152 | — |
| Reactant | 4-Pyridinylacetone | HCID 80552 | — |
| Product | Milrinone | HCID 4197 | — |
Reaction Steps
The process according to claim 1 where 4-pyridinylmethyl methyl ketone and ethoxymethylenemalononitrile are refluxed in ethanol to produce 1,2-dihydro-6-methyl-2-oxo-5-(4-pyridinyl)nicotinonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04347363 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-adc001ab848e4899895bf548738232fd |
| Source note | uspto-grants-1982_08 |