4-{5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-1,2,4-oxadiazol-3-yl}-1H-indole → 3-(3-chloro-1H-indol-4-yl)-5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-1,2,4-oxadiazole

HRID 679600Notes

Reaction equation

HRID 679600 reaction equation
[Cl:1][c:2]1[c:3]2[c:4]([cH:5][cH:6][c:7](-[c:8]3[n:9][c:10](-[c:11]4[cH:12][cH:13][c:14]([O:15][CH:16]([CH3:17])[CH3:18])[c:19]([Cl:20])[cH:21]4)[o:22][n:23]3)[cH:24]2)[nH:25][cH:26]1.[c:27]1(-[c:33]2[cH:34][c:35](-[c:42]3[n:43][c:44](-[c:47]4[c:48]5[cH:49][cH:50][nH:51][c:52]5[cH:53][cH:54][cH:55]4)[n:45][o:46]3)[s:36][c:37]2[C:38]([F:39])([F:40])[F:41])[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[Cl:1][c:49]1[c:48]2[c:47](-[c:44]3[n:43][c:42](-[c:35]4[cH:34][c:33](-[c:27]5[cH:28][cH:29][cH:30][cH:31][cH:32]5)[c:37]([C:38]([F:39])([F:40])[F:41])[s:36]4)[o:46][n:45]3)[cH:55][cH:54][cH:53][c:52]2[nH:51][cH:50]1

Participants

3

Reactant 2

HCID 251104144-{5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-1,2,4-oxadiazol-3-yl}-1H-indoleHCID 593183613-Chloro-5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-1H-indole

Product 1

HCID 593183703-(3-chloro-1H-indol-4-yl)-5-[4-phenyl-5-(trifluoromethyl)thiophen-2-yl]-1,2,4-oxadiazole

Sources & evidence

ORD record
ord-746ee87d64bb4512a09c1d6b6f3ea87c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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