Acetonitrile → 4-{7-[Bis-(2-trimethylsilanyl-ethoxymethyl)-amino]-3-iodo-pyrazolo[1,5-a]pyrimidin-5-yl}-cyclohexanecarboxylic acid methyl ester

HRID 680181Notes

Reaction equation

HRID 680181 reaction equation
[CH3:45][C:46]#[N:47].[CH3:9][O:10][C:11](=[O:12])[CH:13]1[CH2:14][CH2:15][CH:16]([c:19]2[n:20][c:21]3[n:22]([c:23]([N:25]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:39])([CH3:40])[CH3:41])[cH:24]2)[n:42][cH:43][cH:44]3)[CH2:17][CH2:18]1.[I:1][N:2]1[C:3](=[O:4])[CH2:5][CH2:6][C:7]1=[O:8]>>[I:1][c:44]1[c:21]2[n:20][c:19]([CH:16]3[CH2:15][CH2:14][CH:13]([C:11]([O:10][CH3:9])=[O:12])[CH2:18][CH2:17]3)[cH:24][c:23]([N:25]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[CH2:34][O:35][CH2:36][CH2:37][Si:38]([CH3:39])([CH3:40])[CH3:41])[n:22]2[n:42][cH:43]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 120273N-IodosuccinimideHCID 66896532HCID 66896532, compound

Product 1

HCID 667384164-{7-[Bis-(2-trimethylsilanyl-ethoxymethyl)-amino]-3-iodo-pyrazolo[1,5-a]pyrimidin-5-yl}-cyclohexanecarboxylic acid methyl ester

Sources & evidence

ORD record
ord-24fa5db1cbfa47c7a4ef53cd1c569f7b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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