Morpholine → Methyl 3-methyl-4-morpholin-4-ylbenzoate

HRID 680488Notes

Reaction equation

HRID 680488 reaction equation
[Br:1][c:2]1[c:3]([CH3:12])[cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[C:13](=[O:14])([O-:15])[O-:16].[CH2:19]1[CH2:20][O:21][CH2:22][CH2:23][NH:24]1.[CH2:71]1[O:72][CH2:73][CH2:74][O:75][CH2:76]1.[Cs+:17].[Cs+:18].[cH:25]1[cH:26][cH:27][c:28]([P:29]([c:30]2[cH:31][cH:32][c:33]3[c:34]([cH:35][cH:36][cH:37][cH:38]3)[c:39]2-[c:40]2[c:41]3[c:42]([cH:43][cH:44][cH:45][cH:46]3)[cH:47][cH:48][c:49]2[P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:69][cH:70]1>>[c:2]1([N:24]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[c:3]([CH3:12])[cH:4][c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 8083MorpholineHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 634876Binap, (A+-)-HCID 3294148Methyl 4-bromo-3-methylbenzoate

Product 1

HCID 67528858Methyl 3-methyl-4-morpholin-4-ylbenzoate

Sources & evidence

ORD record
ord-de32b78355434bdeb9f9a8727a19c35a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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