Methanol → 2-Amino-alpha-(3-tert-butoxycarbonylaminomethylphenyl)-5-isobutyloxybenzyl alcohol

HRID 680820Notes

Reaction equation

[BH4-:30].[CH3:32][OH:33].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[c:6]2[cH:7][c:8]([CH2:12][NH:13][C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[cH:9][cH:10][cH:11]2)[cH:21][c:22]([O:25][CH2:26][CH:27]([CH3:28])[CH3:29])[cH:23][cH:24]1.[Na+:31]>>[NH2:1][c:2]1[c:3]([CH:4]([OH:5])[c:6]2[cH:7][c:8]([CH2:12][NH:13][C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[cH:9][cH:10][cH:11]2)[cH:21][c:22]([O:25][CH2:26][CH:27]([CH3:28])[CH3:29])[cH:23][cH:24]1

Participants

Reactant 4

HCID 887Methanol

HCID 923Sodium ion

HCID 28123Borohydride

HCID 183153652-Amino-3'-tert-butoxycarbonylaminomethyl-5-isobutyloxy-benzophenone

Product 1

HCID 542166762-Amino-alpha-(3-tert-butoxycarbonylaminomethylphenyl)-5-isobutyloxybenzyl alcohol

Sources & evidence

ORD record: ord-151ac0b2c10b4285a314c8ab8b5341b0
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (3/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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