2,5-Difluorobenzoyl chloride → (2,5-difluorophenyl)-(7-iodo-3,4-dihydro-2H-pyrido[2,3-b]pyrazin-1-yl)methanone
Reaction equation
[F:12][c:13]1[c:14]([C:15](=[O:16])[Cl:17])[cH:18][c:19]([F:22])[cH:20][cH:21]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([n:10][cH:11]1)[NH:6][CH2:7][CH2:8][NH:9]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([n:10][cH:11]1)[NH:6][CH2:7][CH2:8][N:9]2[C:15]([c:14]1[c:13]([F:12])[cH:21][cH:20][c:19]([F:22])[cH:18]1)=[O:16]Participants
3
Sources & evidence
- ORD record
- ord-f3bbe5b9e7524c26800f2e5246640e9d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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