3,5-Difluorobenzyl Chloroformate → (2'-{[(3,5-Difluoro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6'-methoxy-biphenyl-3-yl)-acetic acid methyl ester

HRID 681072Notes

Reaction equation

HRID 681072 reaction equation
[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:11]2[c:12]([CH2:19][NH:20][CH2:21][CH3:22])[cH:13][cH:14][cH:15][c:16]2[O:17][CH3:18])[cH:8][cH:9][cH:10]1)=[O:23].[Cl:24][C:25](=[O:26])[O:27][CH2:28][c:29]1[cH:30][c:31]([F:36])[cH:32][c:33]([F:35])[cH:34]1>>[CH3:1][O:2][C:3]([CH2:4][c:5]1[cH:6][c:7](-[c:11]2[c:12]([CH2:19][N:20]([CH2:21][CH3:22])[C:25](=[O:26])[O:27][CH2:28][c:29]3[cH:30][c:31]([F:36])[cH:32][c:33]([F:35])[cH:34]3)[cH:13][cH:14][cH:15][c:16]2[O:17][CH3:18])[cH:8][cH:9][cH:10]1)=[O:23]

Participants

3

Reactant 2

HCID 574588023,5-Difluorobenzyl ChloroformateHCID 58149181(2'-Ethylaminomethyl-6'-methoxy-biphenyl-3-yl)-acetic acid methyl ester

Product 1

HCID 58148900(2'-{[(3,5-Difluoro-benzyloxycarbonyl)-ethyl-amino]-methyl}-6'-methoxy-biphenyl-3-yl)-acetic acid methyl ester

Sources & evidence

ORD record
ord-240cc15521b646b6bc47827cfd7d97ea
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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