6-Bromo-4-[4-(4-trifluoromethylsulfonylphenoxy)piperidin-1-yl] quinoline → 4-[4-(4-trifluoromethylsulfonylphenoxy)piperidin-1-yl]-6-(3-trifluoromethyl-1-trityl-1H-pyrazol-4-yl) quinoline
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([N:12]3[CH2:13][CH2:14][CH:15]([O:18][c:19]4[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[C:28]([F:29])([F:30])[F:31])[cH:23][cH:24]4)[CH2:16][CH2:17]3)[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[F:32][C:33]([c:34]1[n:35][n:36]([C:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:37][c:38]1[B:39]([OH:40])[OH:41])([F:61])[F:62]>>[c:2]1(-[c:38]2[c:34]([C:33]([F:32])([F:61])[F:62])[n:35][n:36]([C:42]([c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)([c:49]3[cH:50][cH:51][cH:52][cH:53][cH:54]3)[c:55]3[cH:56][cH:57][cH:58][cH:59][cH:60]3)[cH:37]2)[cH:3][c:4]2[c:5]([N:12]3[CH2:13][CH2:14][CH:15]([O:18][c:19]4[cH:20][cH:21][c:22]([S:25](=[O:26])(=[O:27])[C:28]([F:29])([F:30])[F:31])[cH:23][cH:24]4)[CH2:16][CH2:17]3)[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-fa37f4d4bbe7409a89a9fb680b32f5f9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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