3-Chlorobenzoic Acid → 3-(2,3-Difluorophenyl)-1-propylpyrrolidin-3-OL 1-oxide
Reaction equation
[Cl:18][c:19]1[cH:20][c:21]([C:26](=[O:23])[OH:27])[cH:22][cH:24][cH:25]1.[Cl:28][CH2:29][Cl:30].[F:1][c:2]1[c:3]([C:9]2([OH:17])[CH2:10][N:11]([CH2:14][CH2:15][CH3:16])[CH2:12][CH2:13]2)[cH:4][cH:5][cH:6][c:7]1[F:8]>>[F:1][c:2]1[c:3]([C:9]2([OH:17])[CH2:10][N+:11]([CH2:14][CH2:15][CH3:16])([O-:23])[CH2:12][CH2:13]2)[cH:4][cH:5][cH:6][c:7]1[F:8]Participants
4
Sources & evidence
- ORD record
- ord-98ae820d76cf43018112cde9dc89fa2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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