1,4-Dioxane → 5-Chloro-4-[(4-chlorophenylthio)(2,5-difluorophenyl)methyl]-2-[2-(pyridin-4-yl)ethylamino]pyridine

HRID 681274Notes

Reaction equation

HRID 681274 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:25])[c:6]([CH:8]([c:9]2[c:10]([F:16])[cH:11][cH:12][c:13]([F:15])[cH:14]2)[S:17][c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[cH:7]1.[NH2:26][CH2:27][CH2:28][c:29]1[cH:30][cH:31][n:32][cH:33][cH:34]1.[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1>>[c:2]1([NH:26][CH2:27][CH2:28][c:29]2[cH:30][cH:31][n:32][cH:33][cH:34]2)[n:3][cH:4][c:5]([Cl:25])[c:6]([CH:8]([c:9]2[c:10]([F:16])[cH:11][cH:12][c:13]([F:15])[cH:14]2)[S:17][c:18]2[cH:19][cH:20][c:21]([Cl:24])[cH:22][cH:23]2)[cH:7]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 832754-PyridineethanamineHCID 231145672,5-Dichloro-4-[(4-chlorophenylthio)-(2,5-difluorophenyl)methyl]pyridine

Product 1

HCID 231148365-Chloro-4-[(4-chlorophenylthio)(2,5-difluorophenyl)methyl]-2-[2-(pyridin-4-yl)ethylamino]pyridine

Sources & evidence

ORD record
ord-6ca1a5e73f684adea1a22b3b5f38a3eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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