Dichloromethane → 2-(Dimethylamino)ethyl 3-(3-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)isoquinolin-1-yl)benzoate
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][OH:5])[CH3:6].[Cl:43][CH2:44][Cl:45].[F:7][C:8]1([F:42])[O:9][c:10]2[c:11]([cH:13][cH:14][c:15]([C:17]3([C:20](=[O:21])[NH:22][c:23]4[n:24][c:25](-[c:33]5[cH:34][c:35]([C:36](=[O:37])[Cl:38])[cH:39][cH:40][cH:41]5)[c:26]5[cH:27][cH:28][cH:29][cH:30][c:31]5[cH:32]4)[CH2:18][CH2:19]3)[cH:16]2)[O:12]1>>[CH3:1][N:2]([CH2:3][CH2:4][O:5][C:36]([c:35]1[cH:34][c:33](-[c:25]2[n:24][c:23]([NH:22][C:20]([C:17]3([c:15]4[cH:14][cH:13][c:11]5[c:10]([cH:16]4)[O:9][C:8]([F:7])([F:42])[O:12]5)[CH2:18][CH2:19]3)=[O:21])[cH:32][c:31]3[c:26]2[cH:27][cH:28][cH:29][cH:30]3)[cH:41][cH:40][cH:39]1)=[O:37])[CH3:6]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-5a2f9f3dbe7943cab784f15debc182a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…