3-(methylsulfonyl)pyrrolidine → (2-(1H-indazol-4-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)(3-(methylsulfonyl)pyrrolidin-1-yl)methanone
Reaction equation
[CH3:28][S:29](=[O:30])(=[O:31])[CH:32]1[CH2:33][NH:34][CH2:35][CH2:36]1.[nH:1]1[n:2][cH:3][c:4]2[c:5](-[c:10]3[n:11][c:12]([N:22]4[CH2:23][CH2:24][O:25][CH2:26][CH2:27]4)[c:13]4[c:14]([n:15]3)[cH:16][c:17]([C:19](=[O:20])[OH:21])[s:18]4)[cH:6][cH:7][cH:8][c:9]12>>[nH:1]1[n:2][cH:3][c:4]2[c:5](-[c:10]3[n:11][c:12]([N:22]4[CH2:23][CH2:24][O:25][CH2:26][CH2:27]4)[c:13]4[c:14]([n:15]3)[cH:16][c:17]([C:19](=[O:21])[N:34]3[CH2:33][CH:32]([S:29]([CH3:28])(=[O:30])=[O:31])[CH2:36][CH2:35]3)[s:18]4)[cH:6][cH:7][cH:8][c:9]12Participants
3
Sources & evidence
- ORD record
- ord-5f5999019c954ce08af276fbd0112f16
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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