1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carbonitrile → 1-phenylethyl N-[5-[4-[4-(1-cyanocyclopropyl)phenyl]phenyl]-3-methyl-1,2-oxazol-4-yl]carbamate

HRID 681498Notes

Reaction equation

HRID 681498 reaction equation
[CH3:26][C:27]1([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32][B:33]([c:34]2[cH:35][cH:36][c:37]([C:40]3([C:43]#[N:44])[CH2:41][CH2:42]3)[cH:38][cH:39]2)[O:45]1.[c:1]1([CH:7]([CH3:8])[O:9][C:10]([NH:11][c:12]2[c:13]([CH3:24])[n:14][o:15][c:16]2-[c:17]2[cH:18][cH:19][c:20]([Br:23])[cH:21][cH:22]2)=[O:25])[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH:7]([CH3:8])[O:9][C:10]([NH:11][c:12]2[c:13]([CH3:24])[n:14][o:15][c:16]2-[c:17]2[cH:18][cH:19][c:20](-[c:34]3[cH:35][cH:36][c:37]([C:40]4([C:43]#[N:44])[CH2:41][CH2:42]4)[cH:38][cH:39]3)[cH:21][cH:22]2)=[O:25])[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

3

Reactant 2

HCID 534235231-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropane-1-carbonitrileHCID 66660478[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-carbamic acid 1-phenyl-ethyl ester

Product 1

HCID 753007821-phenylethyl N-[5-[4-[4-(1-cyanocyclopropyl)phenyl]phenyl]-3-methyl-1,2-oxazol-4-yl]carbamate

Sources & evidence

ORD record
ord-6c19d9403f58474a8d4c00a3976b4bdf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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