HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 681556Generated: October 31, 2026
Acetonitrile → tert-butyl N-[1-[2-[[5-[2-(2-aminopyrimidin-5-yl)ethynyl]-2-fluorobenzoyl]amino]-4-(trifluoromethyl)phenyl]piperidin-3-yl]-N-methylcarbamate
https://huagongshe.com/reaction/681556
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | Palladium Chloride | HCID 24290 | — |
| Reactant | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| Reactant | 5-Ethynylpyrimidin-2-amine | HCID 16109021 | — |
| Reactant | tert-butyl N-[1-[2-[(2-fluoro-5-iodobenzoyl)amino]-4-(trifluoromethyl)phenyl]piperidin-3-yl]-N-methylcarbamate | HCID 68457850 | — |
| Product | tert-butyl N-[1-[2-[[5-[2-(2-aminopyrimidin-5-yl)ethynyl]-2-fluorobenzoyl]amino]-4-(trifluoromethyl)phenyl]piperidin-3-yl]-N-methylcarbamate | HCID 68457888 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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| ORD ID | ord-241558ac89484ace9180703f8f141a17 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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