Methanol → 1-[2-[4-(4-chlorophenyl)piperazin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]-4-hydroxypyrrolidine-2-carboxylic acid

HRID 681679Notes

Reaction equation

HRID 681679 reaction equation
[CH3:36][OH:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[n:15][c:16]([N:24]4[CH:25]([C:30](=[O:31])[O:32][CH3:33])[CH2:26][CH:27]([OH:29])[CH2:28]4)[c:17]4[c:18]([n:19]3)[CH2:20][CH2:21][S:22]4=[O:23])[CH2:12][CH2:13]2)[cH:6][cH:7]1.[Na+:35].[OH-:34]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([c:14]3[n:15][c:16]([N:24]4[CH:25]([C:30](=[O:31])[OH:32])[CH2:26][CH:27]([OH:29])[CH2:28]4)[c:17]4[c:18]([n:19]3)[CH2:20][CH2:21][S:22]4=[O:23])[CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 178498568HCID 178498568, compound

Product 1

HCID 1785246201-[2-[4-(4-chlorophenyl)piperazin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]-4-hydroxypyrrolidine-2-carboxylic acid

Sources & evidence

ORD record
ord-6c996987624849359907c9a96822bf06
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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