3-Aminophenol → N4-(2,6-dimethoxypyridin-3-yl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine
Reaction equation
[Cl:9][c:10]1[n:11][cH:12][c:13]([F:27])[c:14]([NH:16][c:17]2[c:18]([O:25][CH3:26])[n:19][c:20]([O:23][CH3:24])[cH:21][cH:22]2)[n:15]1.[OH:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][cH:8]1>>[OH:1][c:2]1[cH:3][c:4]([NH:5][c:10]2[n:11][cH:12][c:13]([F:27])[c:14]([NH:16][c:17]3[c:18]([O:25][CH3:26])[n:19][c:20]([O:23][CH3:24])[cH:21][cH:22]3)[n:15]2)[cH:6][cH:7][cH:8]1Participants
3
Sources & evidence
- ORD record
- ord-88433a946b154edf924636bd2e4a73c4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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