HRID68210

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID9526

Methyl trifluoromethanesulfonate

C2H3F3O3S

结构：CC(C)(C)[Si](C)(C)Oc1ccc(OC(=O)c2c3ccccc3nc3ccccc23)cc1

HCID21972276

未命名化合物

PRODUCTS

生成物

结构：C[n+]1c2ccccc2c(C(=O)Oc2ccc(O[Si](C)(C)C(C)(C)C)cc2)c2ccccc21.O=S(=O)([O-])C(F)(F)F

HCID86615371

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

Into a 50 mL round bottom flask equipped with magnetic stirrer under argon atmosphere charged a solution of 1.6 parts of 4-(tert-butyldimethylsilyloxy)phenyl acridin-9-carboxylate in 25 mL of dichloromethane. 3.2 Parts of methyl trifluoromethanesulfonate was added to the solution and stirred for 40 hrs at room temperature. Bright yellow solid was collected by filtration, washed with 2×1 mL of dichloromethane and air dried for 4 hr to yield 1.44 parts of 4-(tert-butyldimethylsilyloxy)phenyl 10-methylacridinium-9-carboxylate trifluoromethanesulfonate having the following structure confirmed by NMR.

WORKUP

后处理

customInto a 50 mL round bottom flask equipped with magnetic stirrer under argon atmosphere
filtrationBright yellow solid was collected by filtration
washwashed with 2×1 mL of dichloromethane and air
customdried for 4 hr

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c19fea5160344d28a3443bb6527dcc16
来源数据集: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08822233B2
来源说明: uspto-grants-2014_09

反应 SMILES

[CH:1]1[C:14]2[C:5](=[N:6][C:7]3[C:12]([C:13]=2[C:15]([O:17][C:18]2[CH:23]=[CH:22][C:21]([O:24][Si:25]([C:28]([CH3:31])([CH3:30])[CH3:29])([CH3:27])[CH3:26])=[CH:20][CH:19]=2)=[O:16])=[CH:11][CH:10]=[CH:9][CH:8]=3)[CH:4]=[CH:3][CH:2]=1.[F:32][C:33]([F:40])([F:39])[S:34]([O:37]C)(=[O:36])=[O:35]>ClCCl>[F:32][C:33]([F:40])([F:39])[S:34]([O-:37])(=[O:36])=[O:35].[CH3:33][N+:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:13]([C:15]([O:17][C:18]2[CH:19]=[CH:20][C:21]([O:24][Si:25]([C:28]([CH3:31])([CH3:30])[CH3:29])([CH3:26])[CH3:27])=[CH:22][CH:23]=2)=[O:16])=[C:14]2[C:5]=1[CH:4]=[CH:3][CH:2]=[CH:1]2