HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 3-tert-Butyldimethylsilyloxybenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-{[tert-Butyl(dimethyl)silyl]oxy}benzoic acid | HCID 18369587 | — |
| Product | 3-tert-Butyldimethylsilyloxybenzoyl chloride | HCID 12448487 | — |
Reaction Steps
Into a 100 mL round bottom flask a mixture of 5 parts of 3-tert-butyldimethylsilyloxybenzoic acid and 25 mL of thionyl chloride was heated at reflux for 90 mins. The reaction mixture was concentrated under reduced pressure to give an oil, yield 5.77 parts of the following structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822233B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-aac3b60ce93f439490fc389da096672e |
| Source note | uspto-grants-2014_09 |