Acetonitrile → 1-[(3SR,4RS)-4-(3,4-Dichloro-phenyl)-pyrrolidin-3-yl]-ethanone

HRID 682667Notes

Reaction equation

HRID 682667 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:21]([CH3:22])=[O:23])[CH:11]([c:13]2[cH:14][c:15]([Cl:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:12]1.[CH3:33][C:34]#[N:35].[Cl:24][C:25]([O:26][CH2:27][C:28]([Cl:29])([Cl:30])[Cl:31])=[O:32]>>[NH:8]1[CH2:9][CH:10]([C:21]([CH3:22])=[O:23])[CH:11]([c:13]2[cH:14][c:15]([Cl:20])[c:16]([Cl:19])[cH:17][cH:18]2)[CH2:12]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 870632,2,2-Trichloroethyl chloroformateHCID 669997301-[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-ethanone

Product 1

HCID 671317481-[(3SR,4RS)-4-(3,4-Dichloro-phenyl)-pyrrolidin-3-yl]-ethanone

Sources & evidence

ORD record
ord-d3a463080b144263a386265202ae4dc6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…