Methanol → 1-N-(4-chlorophenyl)-4-hydroxy-2-N-[4-(3-oxomorpholin-4-yl)phenyl]pyrrolidine-1,2-dicarboxamide

HRID 682873Notes

Reaction equation

HRID 682873 reaction equation
[CH3:46][OH:47].[N+:3]([c:4]1[cH:5][cH:6][c:7]([C:8](=[O:9])[O:12][CH:13]2[CH2:14][N:15]([C:34]([NH:35][c:36]3[cH:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]3)=[O:43])[CH:16]([C:18]([NH:19][c:20]3[cH:21][cH:22][c:23]([N:26]4[C:27](=[O:32])[CH2:28][O:29][CH2:30][CH2:31]4)[cH:24][cH:25]3)=[O:33])[CH2:17]2)[cH:10][cH:11]1)([O-:44])=[O:45].[Na+:2].[OH-:1]>>[OH:12][CH:13]1[CH2:14][N:15]([C:34]([NH:35][c:36]2[cH:37][cH:38][c:39]([Cl:42])[cH:40][cH:41]2)=[O:43])[CH:16]([C:18]([NH:19][c:20]2[cH:21][cH:22][c:23]([N:26]3[C:27](=[O:32])[CH2:28][O:29][CH2:30][CH2:31]3)[cH:24][cH:25]2)=[O:33])[CH2:17]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 66593350[1-[(4-Chlorophenyl)carbamoyl]-5-[[4-(3-oxomorpholin-4-yl)phenyl]carbamoyl]pyrrolidin-3-yl] 4-nitrobenzoate

Product 1

HCID 728126471-N-(4-chlorophenyl)-4-hydroxy-2-N-[4-(3-oxomorpholin-4-yl)phenyl]pyrrolidine-1,2-dicarboxamide

Sources & evidence

ORD record
ord-efd573429c66463192363047b4e83d36
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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