HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexylamine → HCID 66889103, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexylamine | HCID 7965 | — |
| Reactant | 3-(6-methoxy-2-(methylsulfonyl)pyrimidin-4-yl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine | HCID 66888712 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 66889103 | HCID 66889103 | — |
Reaction Steps
A solution of EXAMPLE 1B (6.7 g, 15.1 mmol) and cyclohexanamine (6.90 mL, 60.3 mmol) in dioxane (165 mL) was heated at 100° C. overnight. The mixture was concentrated to afford the crude title compound which was directly used in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822446B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-4a37973380cc40cba6e064adb468c18f |
| Source note | uspto-grants-2014_09 |