Cyclobutanecarbonyl chloride → 1-Cyclobutanecarbonyl-3-(4'-fluoro-biphenyl-4-yloxymethyl)-pyrrolidine-3-carboxylic acid ethyl ester
Reaction equation
[CH2:8]([CH3:9])[O:10][C:11](=[O:12])[C:13]1([CH2:18][O:19][c:20]2[cH:21][cH:22][c:23](-[c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[cH:24][cH:25]2)[CH2:14][NH:15][CH2:16][CH2:17]1.[CH:1]1([C:5](=[O:6])[Cl:7])[CH2:2][CH2:3][CH2:4]1>>[CH:1]1([C:5](=[O:6])[N:15]2[CH2:14][C:13]([C:11]([O:10][CH2:8][CH3:9])=[O:12])([CH2:18][O:19][c:20]3[cH:21][cH:22][c:23](-[c:26]4[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]4)[cH:24][cH:25]3)[CH2:17][CH2:16]2)[CH2:2][CH2:3][CH2:4]1Participants
3
Sources & evidence
- ORD record
- ord-261c3e2aa4974e38b966889fd42db752
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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