HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 131731809, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 131731810 | HCID 131731810 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 131731809 | HCID 131731809 | 79% |
Reaction Steps
By using the procedure described in Step-4 of Example-1 above, and by using tetrabutylammonium salt of trans-3-[N′-(6-sulfooxy-7-oxo-1,6-diaza-bicyclo[3.2.1]octane-2-carbonyl)-hydrazinocarbonyl]-(R)-piperidin-1-carboxylic acid tert-butyl ester (24 gm, 0.032 mmol), dichloromethane (60 ml) and trifluoroacetic acid (60 nil) to provide the title compound in 10 gm quantity as a white solid, in 79% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822450B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-91b0d2104b5442869f2df4f36f513e22 |
| Source note | uspto-grants-2014_09 |