3-(Pyrrolidino)phenylboronic acid → 3-Nitro-N6-(2-{[7-(3-pyrrolidin-1-ylphenyl)[1,2,4]triazolo[1,5-c]pyrimidin-5-yl]amino}-ethyl)pyridine-2,6-diamine

HRID 683636Notes

Reaction equation

HRID 683636 reaction equation
[Cl:1][c:2]1[cH:3][c:4]2[n:5]([c:6]([NH:8][CH2:9][CH2:10][NH:11][c:12]3[cH:13][cH:14][c:15]([N+:19](=[O:20])[O-:21])[c:16]([NH2:18])[n:17]3)[n:7]1)[n:22][cH:23][n:24]2.[N:25]1([c:30]2[cH:31][c:32]([B:36]([OH:37])[OH:38])[cH:33][cH:34][cH:35]2)[CH2:26][CH2:27][CH2:28][CH2:29]1>>[c:2]1(-[c:32]2[cH:31][c:30]([N:25]3[CH2:26][CH2:27][CH2:28][CH2:29]3)[cH:35][cH:34][cH:33]2)[cH:3][c:4]2[n:5]([c:6]([NH:8][CH2:9][CH2:10][NH:11][c:12]3[cH:13][cH:14][c:15]([N+:19](=[O:20])[O-:21])[c:16]([NH2:18])[n:17]3)[n:7]1)[n:22][cH:23][n:24]2

Participants

3

Reactant 2

HCID 41926693-(Pyrrolidino)phenylboronic acidHCID 59312901N6-{2-[(7-Chloro[1,2,4]triazolo[1,5-c]pyrimidin-5-yl)amino]ethyl}-3-nitropyridine-2,6-diamine

Product 1

HCID 593130953-Nitro-N6-(2-{[7-(3-pyrrolidin-1-ylphenyl)[1,2,4]triazolo[1,5-c]pyrimidin-5-yl]amino}-ethyl)pyridine-2,6-diamine

Sources & evidence

ORD record
ord-f90dc22e4e7e40acade5226186a1c38d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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