5-Methylnicotinic acid → N-[5-(4-Chloro-phenyl)-6-cyclobutoxy-pyridin-3-yl]-5-methyl-nicotinamide
Reaction equation
[CH3:20][c:21]1[cH:22][c:23]([C:27](=[O:28])[OH:29])[cH:24][n:25][cH:26]1.[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH2:19])[cH:11][n:12][c:13]2[O:14][CH:15]2[CH2:16][CH2:17][CH2:18]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][c:10]([NH:19][C:27]([c:23]3[cH:22][c:21]([CH3:20])[cH:26][n:25][cH:24]3)=[O:28])[cH:11][n:12][c:13]2[O:14][CH:15]2[CH2:16][CH2:17][CH2:18]2)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-c82fa1be13004b968432f2ec583b0496
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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