HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 683788Generated: October 31, 2026
1,2-Dichloroethane → 1-Cyclopropyl-3-(3-fluoro-4-(2-(5-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea
https://huagongshe.com/reaction/683788
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,2-Dichloroethane | HCID 11 | — |
| Reactant | Bicarbonate Ion | HCID 769 | — |
| Reactant | Sodium ion | HCID 923 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 1-Methyl-4-(piperidin-4-yl)piperazine | HCID 795707 | — |
| Reactant | 6-(7-(4-(3-Cyclopropylureido)-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)nicotinic acid | HCID 67441828 | — |
| Product | 1-Cyclopropyl-3-(3-fluoro-4-(2-(5-(4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl)pyridin-2-yl)thieno[3,2-b]pyridin-7-yloxy)phenyl)urea | HCID 53476396 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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| ORD ID | ord-e6407cae3fd84bfabddbd051ef74a748 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
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