Ethanol → [1-(2-Hydroxy-3-trityloxypropyl)-3-methylpiperidin-4-yl] 2,2-dimethylpropanoate

HRID 683947Notes

Reaction equation

HRID 683947 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][CH2:21][CH:22]1[O:23][CH2:24]1.[CH3:25][CH:26]1[CH2:27][NH:28][CH2:29][CH2:30][CH:31]1[O:32][C:33]([C:34]([CH3:35])([CH3:36])[CH3:37])=[O:38].[CH3:39][CH2:40][OH:41]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][CH2:21][CH:22]([OH:23])[CH2:24][N:28]1[CH2:27][CH:26]([CH3:25])[CH:31]([O:32][C:33]([C:34]([CH3:35])([CH3:36])[CH3:37])=[O:38])[CH2:30][CH2:29]1

Participants

4

Reactant 3

HCID 702EthanolHCID 3465228(R)-trityl glycidyl etherHCID 668421342,2-Dimethyl-propionic acid (3RS,4RS)-3-methyl-piperidin-4-yl ester

Product 1

HCID 72335848[1-(2-Hydroxy-3-trityloxypropyl)-3-methylpiperidin-4-yl] 2,2-dimethylpropanoate

Sources & evidence

ORD record
ord-6c794715a4694d88a44ef8e8247e925c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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