Pyridine → N1-(4-{4-amino-1-[1-(1-methylpiperidin-4-yl)piperidin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl}-2-methoxyphenyl)-4-(trifluoromethoxy)benzamide
Reaction equation
[Cl:53][CH2:54][Cl:55].[F:33][C:34]([O:35][c:36]1[cH:37][cH:38][c:39]([C:42](=[O:43])[Cl:44])[cH:40][cH:41]1)([F:45])[F:46].[NH2:1][c:2]1[c:3]([O:31][CH3:32])[cH:4][c:5](-[c:8]2[n:9][n:10]([CH:18]3[CH2:19][CH2:20][N:21]([CH:24]4[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]4)[CH2:22][CH2:23]3)[c:11]3[n:12][cH:13][n:14][c:15]([NH2:17])[c:16]23)[cH:6][cH:7]1.[cH:47]1[cH:48][cH:49][n:50][cH:51][cH:52]1>>[NH:1]([c:2]1[c:3]([O:31][CH3:32])[cH:4][c:5](-[c:8]2[n:9][n:10]([CH:18]3[CH2:19][CH2:20][N:21]([CH:24]4[CH2:25][CH2:26][N:27]([CH3:30])[CH2:28][CH2:29]4)[CH2:22][CH2:23]3)[c:11]3[n:12][cH:13][n:14][c:15]([NH2:17])[c:16]23)[cH:6][cH:7]1)[C:42]([c:39]1[cH:38][cH:37][c:36]([O:35][C:34]([F:33])([F:45])[F:46])[cH:41][cH:40]1)=[O:43]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4e4557a22cfd48cf918560c8011977a4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…