Acetonitrile → 3-[(4-Chlorophenyl)-[3-[1-(3,5-difluorophenyl)-2-fluoro-2-methylpropyl]azetidin-1-yl]methyl]benzonitrile
Reaction equation
[Br:24][CH:25]([c:26]1[cH:27][c:28]([C:29]#[N:30])[cH:31][cH:32][cH:33]1)[c:34]1[cH:35][cH:36][c:37]([Cl:40])[cH:38][cH:39]1.[C:18](=[O:19])([O-:20])[O-:21].[CH3:41][C:42]#[N:43].[Cs+:22].[Cs+:23].[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10]([CH3:11])([CH3:12])[F:13])[CH:14]2[CH2:15][NH:16][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([CH:9]([C:10]([CH3:11])([CH3:12])[F:13])[CH:14]2[CH2:15][N:16]([CH:25]([c:26]3[cH:27][c:28]([C:29]#[N:30])[cH:31][cH:32][cH:33]3)[c:34]3[cH:35][cH:36][c:37]([Cl:40])[cH:38][cH:39]3)[CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6e06f0c1adfc4eaeb5bbd0af8c0f0020
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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