2-Pyridinemethanamine → 2-[3-[(4-fluorophenyl)methyl]-5-methyl-2-oxoimidazolidin-1-yl]-4-methyl-N-(pyridin-2-ylmethyl)-1,3-thiazole-5-carboxamide
Reaction equation
[F:17][c:18]1[cH:19][cH:20][c:21]([CH2:22][N:23]2[CH:24]([CH3:25])[CH2:26][N:27]([c:28]3[s:29][c:30]([C:31]([OH:32])=[O:33])[c:34]([CH3:35])[n:36]3)[C:37]2=[O:38])[cH:39][cH:40]1.[F:41][c:42]1[cH:43][cH:44][c:45]([CH2:46][N:47]2[C:48](=[O:62])[N:49]([c:53]3[s:54][c:55]([C:59](=[O:60])[OH:61])[c:56]([CH3:58])[n:57]3)[CH:50]([CH3:52])[CH2:51]2)[cH:63][cH:64]1.[n:1]1[cH:2][cH:3][cH:4][c:5]([CH2:6][NH2:7])[cH:8]1.[n:9]1[c:10]([CH2:15][NH2:16])[cH:11][cH:12][cH:13][cH:14]1>>[n:9]1[c:10]([CH2:15][NH:16][C:59]([c:55]2[s:54][c:53]([N:49]3[C:48](=[O:62])[N:47]([CH2:46][c:45]4[cH:44][cH:43][c:42]([F:41])[cH:64][cH:63]4)[CH2:51][CH:50]3[CH3:52])[n:57][c:56]2[CH3:58])=[O:60])[cH:11][cH:12][cH:13][cH:14]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-4c77524dda1845249f70e08c54255fd7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…