Bromide ion → 2,6-Difluoro-N-(4-(1-hydroxyethyl)-5-(3-(trifluoromethyl)phenyl)thiazol-2-yl)benzamide
Reaction equation
[Br-:29].[CH3:30][Mg+:31].[F:1][c:2]1[cH:3][cH:4][cH:5][c:6]([F:7])[c:8]1[C:9]([NH:10][c:11]1[s:12][c:13](-[c:14]2[cH:15][cH:16][cH:17][c:18]([C:19]([F:20])([F:21])[F:22])[cH:23]2)[c:24]([CH:25]=[O:26])[n:27]1)=[O:28].[F:32][c:33]1[c:34]([C:35](=[O:36])[NH:37][c:38]2[s:39][c:40](-[c:47]3[cH:48][c:49]([C:53]([F:54])([F:55])[F:56])[cH:50][cH:51][cH:52]3)[c:41]([C:43]([CH3:44])([CH3:45])[OH:46])[n:42]2)[c:57]([F:61])[cH:58][cH:59][cH:60]1>>[F:32][c:33]1[c:34]([C:35](=[O:36])[NH:37][c:38]2[s:39][c:40](-[c:47]3[cH:48][c:49]([C:53]([F:54])([F:55])[F:56])[cH:50][cH:51][cH:52]3)[c:41]([CH:43]([CH3:44])[OH:46])[n:42]2)[c:57]([F:61])[cH:58][cH:59][cH:60]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-31316df46ca64d4abf8fd9d27d04eea7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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