Potassium Cation → 3'-(2,2-Dimethylpropoxy)-7'-(2-fluoro-3-pyridinyl)spiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

HRID 684648Notes

Reaction equation

HRID 684648 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:19]([cH:20][cH:21]1)[O:18][c:7]1[c:6]([cH:11][c:10]([O:12][CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[n:9][cH:8]1)[C:5]21[CH2:22][O:23][CH2:24][C:25]([NH2:27])=[N:26]1.[F:28][c:29]1[n:30][cH:31][cH:32][cH:33][c:34]1[B:35]([OH:36])[OH:37].[K+:43].[K+:44].[K+:45].[P:38]([O-:39])([O-:40])([O-:41])=[O:42]>>[c:2]1(-[c:34]2[c:29]([F:28])[n:30][cH:31][cH:32][cH:33]2)[cH:3][c:4]2[c:19]([cH:20][cH:21]1)[O:18][c:7]1[c:6]([cH:11][c:10]([O:12][CH2:13][C:14]([CH3:15])([CH3:16])[CH3:17])[n:9][cH:8]1)[C:5]21[CH2:22][O:23][CH2:24][C:25]([NH2:27])=[N:26]1

Participants

5

Reactant 4

HCID 813Potassium Cation3×HCID 1061PhosphateHCID 27832702-Fluoropyridine-3-boronic acidHCID 674400417'-Bromo-3'-(2,2-dimethylpropoxy)spiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

Product 1

HCID 533902173'-(2,2-Dimethylpropoxy)-7'-(2-fluoro-3-pyridinyl)spiro[2,6-dihydro-1,4-oxazine-5,5'-chromeno[2,3-c]pyridine]-3-amine

Sources & evidence

ORD record
ord-4f1c50f08d9040eca6f322b35ff2aa2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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