Dimethylamine → 4-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine

HRID 684773Notes

Reaction equation

HRID 684773 reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[cH:12][n:13][c:14]([F:16])[cH:15]3)[cH:17][cH:18][cH:19]1.[CH3:20][NH:21][CH3:22].[CH3:23][CH2:24][OH:25]>>[Br:1][c:2]1[cH:3][c:4]([NH:5][c:6]2[c:7]3[c:8]([n:9][cH:10][n:11]2)[cH:12][n:13][c:14]([N:21]([CH3:20])[CH3:22])[cH:15]3)[cH:17][cH:18][cH:19]1

Participants

4

Reactant 3

HCID 674DimethylamineHCID 702EthanolHCID 5328260N-(3-bromophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine

Product 1

HCID 53282614-N-(3-bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine

Sources & evidence

ORD record
ord-3d8e98b6ce804605942a65ff8c46f505
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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