2-Chloro-5-(chloromethyl)thiophene → 4-[1-(5-chloro-thiophen-2-ylmethyl)-6-fluoro-1H-indol-3-yl]-piperidine-1-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][nH:14][c:15]3[cH:16][c:17]([F:21])[cH:18][cH:19][c:20]23)[CH2:10][CH2:11]1.[Cl:22][c:23]1[s:24][c:25]([CH2:28][Cl:29])[cH:26][cH:27]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[N:6]1[CH2:7][CH2:8][CH:9]([c:12]2[cH:13][n:14]([CH2:28][c:25]3[s:24][c:23]([Cl:22])[cH:27][cH:26]3)[c:15]3[cH:16][c:17]([F:21])[cH:18][cH:19][c:20]23)[CH2:10][CH2:11]1Participants
3
Sources & evidence
- ORD record
- ord-6622c3d3f90d4b5b93ff4b48f223087d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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