3-Pyridinemethanamine → 2-(3-((2,2-difluorocyclopropyl)methyl)-2-oxoimidazolidin-1-yl)-4-methyl-N-(thiazol-5-ylmethyl)thiazole-5-carboxamide
Reaction equation
[F:16][C:17]1([F:36])[CH:18]([CH2:20][N:21]2[C:22](=[O:35])[N:23]([c:26]3[s:27][c:28]([C:32](=[O:33])[OH:34])[c:29]([CH3:31])[n:30]3)[CH2:24][CH2:25]2)[CH2:19]1.[NH2:1][CH2:2][c:3]1[cH:4][n:5][cH:6][cH:7][cH:8]1.[s:9]1[cH:10][n:11][cH:12][c:13]1[CH2:14][NH2:15]>>[s:9]1[cH:10][n:11][cH:12][c:13]1[CH2:14][NH:15][C:32]([c:28]1[s:27][c:26]([N:23]2[C:22](=[O:35])[N:21]([CH2:20][CH:18]3[C:17]([F:16])([F:36])[CH2:19]3)[CH2:25][CH2:24]2)[n:30][c:29]1[CH3:31])=[O:34]Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-b8121b78b5c44f41a958024489ca11c7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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