2,4-Dichloro-5-fluoropyrimidine → 2-chloro-N4-(2,6-dimethoxypyridin-3-yl)-5-fluoro-4-pyrimidineamine

HRID 685572Notes

Reaction equation

HRID 685572 reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[NH2:10][c:11]1[c:12]([O:19][CH3:20])[n:13][c:14]([O:17][CH3:18])[cH:15][cH:16]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:10][c:11]2[c:12]([O:19][CH3:20])[n:13][c:14]([O:17][CH3:18])[cH:15][cH:16]2)[n:7]1

Participants

3

Reactant 2

HCID 2507052,4-Dichloro-5-fluoropyrimidineHCID 5930052,6-Dimethoxypyridin-3-amine

Product 1

HCID 220606582-chloro-N4-(2,6-dimethoxypyridin-3-yl)-5-fluoro-4-pyrimidineamine

Sources & evidence

ORD record
ord-2223e88751d84dc1a86bacf2270dd25a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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