Toluene → tert-Butyl 2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepine-4(5H)-carboxylate

HRID 685589Notes

Reaction equation

HRID 685589 reaction equation
[CH3:1][O:2][C:3]([CH2:4][N:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[CH2:13][c:14]1[c:15]([NH2:20])[cH:16][cH:17][cH:18][cH:19]1)=[O:21].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[OH:22][n:23]1[c:24]2[c:25]([cH:26][cH:27][cH:28][cH:29]2)[n:30][n:31]1>>[O:2]=[C:3]1[CH2:4][N:5]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[CH2:13][c:14]2[c:15]([cH:16][cH:17][cH:18][cH:19]2)[NH:20]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 757711-HydroxybenzotriazoleHCID 68630241[(2-Amino-benzyl)-tert-butoxycarbonyl-amino]acetic acid methyl ester

Product 1

HCID 22632545tert-Butyl 2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepine-4(5H)-carboxylate

Sources & evidence

ORD record
ord-3e00a35abf7a4442ab8d9616d909b1d7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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