Dimethyl Sulfoxide → 2-(3-methyl-5-isoquinolinyl)-N-[4-(trifluoromethyl)benzyl]acetamide
Reaction equation
[CH3:1][c:2]1[n:3][cH:4][c:5]2[cH:6][cH:7][cH:8][c:9]([CH2:12][C:13](=[O:14])[OH:15])[c:10]2[cH:11]1.[CH3:41][S:42]([CH3:43])=[O:44].[F:16][C:17]([c:18]1[cH:19][cH:20][c:21]([CH2:22][NH2:23])[cH:24][cH:25]1)([F:26])[F:27].[F:28][C:29]([F:30])([F:31])[O:32][c:33]1[cH:34][cH:35][c:36]([CH2:37][NH2:38])[cH:39][cH:40]1>>[CH3:1][c:2]1[n:3][cH:4][c:5]2[cH:6][cH:7][cH:8][c:9]([CH2:12][C:13](=[O:15])[NH:23][CH2:22][c:21]3[cH:20][cH:19][c:18]([C:17]([F:16])([F:26])[F:27])[cH:25][cH:24]3)[c:10]2[cH:11]1Participants
5
Sources & evidence
- ORD record
- ord-0266536a4e2f412e98d8532eab825efc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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