HCID 67164115, compound → HCID 67163333, compound

HRID 68628Notes

Reaction equation

HRID 68628 reaction equation
[CH3:1][Si:2]([CH3:60])([CH3:59])[CH2:3][CH2:4][O:5][CH2:6][N:7]1[CH:11]=[CH:10][N:9]=[C:8]1[CH2:12][N:13]([CH2:45][C:46]1[N:47]([CH2:51][O:52][CH2:53][CH2:54][Si:55]([CH3:58])([CH3:57])[CH3:56])[CH:48]=[CH:49][N:50]=1)[C:14]([C:16]1[CH:44]=[CH:43][C:19]([CH2:20][N:21]([CH2:32][CH2:33][CH2:34][CH2:35][N:36]([CH2:40][CH2:41][CH3:42])[CH2:37][CH2:38][CH3:39])C(=O)OCC2C=CC=CC=2)=[CH:18][CH:17]=1)=[O:15]>[C].[Pd]>[CH2:40]([N:36]([CH2:37][CH2:38][CH3:39])[CH2:35][CH2:34][CH2:33][CH2:32][NH:21][CH2:20][C:19]1[CH:18]=[CH:17][C:16]([C:14]([N:13]([CH2:45][C:46]2[N:47]([CH2:51][O:52][CH2:53][CH2:54][Si:55]([CH3:56])([CH3:58])[CH3:57])[CH:48]=[CH:49][N:50]=2)[CH2:12][C:8]2[N:7]([CH2:6][O:5][CH2:4][CH2:3][Si:2]([CH3:1])([CH3:59])[CH3:60])[CH:11]=[CH:10][N:9]=2)=[O:15])=[CH:44][CH:43]=1)[CH2:41][CH3:42]

Participants

3

Reactant 1

HCID 67164115HCID 67164115, compound

Product 1

HCID 67163333HCID 67163333, compound

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

The same procedure as a series of reactions of Example 2 was carried out, except that the compound 8 was used in place of the compound 1 and 10% palladium carbon was used in place of 20% palladium hydroxide carbon, to obtain the title compound having the following physical properties.

Sources & evidence

ORD record
ord-ee98fc2506c44fa18ca0d2b0858db56d
Source dataset
uspto-grants-2014_09
Patent number
US08822459B2

Reaction notes

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