HCID 67163511, compound → HCID 67163688, compound

HRID 68631Notes

Reaction equation

HRID 68631 reaction equation
[CH3:1][Si:2]([CH3:51])([CH3:50])[CH2:3][CH2:4][O:5][CH2:6][N:7]1[CH:11]=[CH:10][N:9]=[C:8]1[CH2:12][N:13]([CH2:36][C:37]1[N:38]([CH2:42][O:43][CH2:44][CH2:45][Si:46]([CH3:49])([CH3:48])[CH3:47])[CH:39]=[CH:40][N:41]=1)[C:14]([C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[CH2:22][N:21](C(OCC1C=CC=CC=1)=O)[CH2:20][CH2:19]2)=[O:15]>[C].[Pd]>[CH3:1][Si:2]([CH3:51])([CH3:50])[CH2:3][CH2:4][O:5][CH2:6][N:7]1[CH:11]=[CH:10][N:9]=[C:8]1[CH2:12][N:13]([CH2:36][C:37]1[N:38]([CH2:42][O:43][CH2:44][CH2:45][Si:46]([CH3:49])([CH3:48])[CH3:47])[CH:39]=[CH:40][N:41]=1)[C:14]([C:16]1[CH:17]=[C:18]2[C:23](=[CH:24][CH:25]=1)[CH2:22][NH:21][CH2:20][CH2:19]2)=[O:15]

Participants

3

Reactant 1

HCID 67163511HCID 67163511, compound

Product 1

HCID 67163688HCID 67163688, compound

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

The same procedure as a series of reactions of Example 2 was carried out, except that the compound 12 was used in place of the compound 1 and 10% palladium carbon was used in place of 20% palladium hydroxide carbon, to obtain the title compound having the following physical properties.

Sources & evidence

ORD record
ord-17c4a5fe3d314bc59fdf6e08c33552a2
Source dataset
uspto-grants-2014_09
Patent number
US08822459B2

Reaction notes

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