HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N-dipropylbutane-1,4-diamine → N-[4-({[4-(dipropylamino)butyl]amino}methyl)benzyl]-N-(1H-imidazol-2-ylmethyl)-1H-imidazole-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N-dipropylbutane-1,4-diamine | HCID 7138396 | — |
| Reactant | 1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazole-2-carbaldehyde | HCID 13600235 | — |
| Reactant | N-(4-formylbenzyl)-N-(1H-imidazol-2-ylmethyl)-1H-imidazole-2-carboxamide | HCID 86632126 | — |
| Product | N-[4-({[4-(dipropylamino)butyl]amino}methyl)benzyl]-N-(1H-imidazol-2-ylmethyl)-1H-imidazole-2-carboxamide | HCID 59649556 | — |
Reaction Steps
The same procedure as a series of reactions of Example 1 was carried out, except that the compound 18 was used in place of 1-({[2-(trimethylsilyl)ethyloxy]methyl}-1H-imidazole-2-carboaldehyde and N,N-dipropyl-1,4-butanediamine was used in place of {[4-(methyloxy)phenyl]methyl}amine, to obtain the title compound having the following physical properties.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08822459B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-29c53b03a88c41fc8b05284b39e04e04 |
| Source note | uspto-grants-2014_09 |