反应详情

The same procedure as a series of reactions of Example 1 was carried out, except that the compound 22 was used in place of 1-({[2-(trimethylsilyl)ethyloxy]methyl}-1H-imidazole-2-carboaldehyde and [(1-methyl-1H-imidazol-2-yl)methyl]amine was used in place of {[4-(methyloxy)phenyl]methyl}amine to obtain ({2-[4-(dipropylamino)butyl]-1,2,3,4-tetrahydro-6-isoquinolinyl}methyl)[(1-methyl-1H-imidazol-2-yl)methyl]amine (compound 23-a). The same procedure as a series of reactions of Example 17 was carried out, except that the obtained compound 23-a was used in place of the compound 16, to obtain the title compound having the following physical properties.