4-Formylbenzoic acid → 4-formyl-N,N-bis[(1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazol-2-yl)methyl]benzamide
Reaction equation
[CH3:1][Si:2]([CH3:29])([CH3:28])[CH2:3][CH2:4][O:5][CH2:6][N:7]1[CH:11]=[CH:10][N:9]=[C:8]1[CH2:12][NH:13][CH2:14][C:15]1[N:16]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:27])([CH3:26])[CH3:25])[CH:17]=[CH:18][N:19]=1.[CH:30]([C:32]1[CH:40]=[CH:39][C:35]([C:36](O)=[O:37])=[CH:34][CH:33]=1)=[O:31]>>[CH:30]([C:32]1[CH:40]=[CH:39][C:35]([C:36]([N:13]([CH2:14][C:15]2[N:16]([CH2:20][O:21][CH2:22][CH2:23][Si:24]([CH3:27])([CH3:26])[CH3:25])[CH:17]=[CH:18][N:19]=2)[CH2:12][C:8]2[N:7]([CH2:6][O:5][CH2:4][CH2:3][Si:2]([CH3:29])([CH3:28])[CH3:1])[CH:11]=[CH:10][N:9]=2)=[O:37])=[CH:34][CH:33]=1)=[O:31]Participants
3
Procedure
The same procedure as a series of reactions of Example 17 was carried out, except that the compound 2 was used in place of the compound 16 and 4-formylbenzoic acid was used in place of 1H-imidazole-2-carboxylic acid, to obtain the title compound having the following physical properties.
Sources & evidence
- ORD record
- ord-a4d3359abd7c4d25a96430fdac537b9a
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08822459B2
Reaction notes
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