Methanol → tert-butyl N-[4-(3,5-difluorophenyl)-3-[[3-(1,1-dioxothiazinan-2-yl)-5-(1-hydroxyethyl)benzoyl]amino]-2-hydroxybutyl]-N-[(3-methoxyphenyl)methyl]carbamate
Reaction equation
[BH4-:51].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][c:9]1[cH:10][c:11]([O:15][CH3:16])[cH:12][cH:13][cH:14]1)[CH2:17][CH:18]([CH:19]([CH2:20][c:21]1[cH:22][c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]1)[NH:29][C:30]([c:31]1[cH:32][c:33]([C:45]([CH3:46])=[O:47])[cH:34][c:35]([N:37]2[S:38](=[O:43])(=[O:44])[CH2:39][CH2:40][CH2:41][CH2:42]2)[cH:36]1)=[O:48])[OH:49])=[O:50].[CH3:53][OH:54].[Na+:52]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH2:8][c:9]1[cH:10][c:11]([O:15][CH3:16])[cH:12][cH:13][cH:14]1)[CH2:17][CH:18]([CH:19]([CH2:20][c:21]1[cH:22][c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]1)[NH:29][C:30]([c:31]1[cH:32][c:33]([CH:45]([CH3:46])[OH:47])[cH:34][c:35]([N:37]2[S:38](=[O:43])(=[O:44])[CH2:39][CH2:40][CH2:41][CH2:42]2)[cH:36]1)=[O:48])[OH:49])=[O:50]Participants
5
Sources & evidence
- ORD record
- ord-7b71f228cf9743f2a17645b4220d8e61
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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