Acetic Acid → 6,7-dihydrospiro[benzo[1,2-b:4,5-b']difuran-3,3'-indol]-2'(1'H)-one

HRID 686712Notes

Reaction equation

HRID 686712 reaction equation
[CH3:37][C:38](=[O:39])[OH:40].[H:35][H:36].[OH-:41].[OH-:43].[Pd+2:42].[c:1]1([CH:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:29]2)[N:8]2[C:9](=[O:28])[C:10]3([c:11]4[c:12]([cH:15][c:16]5[c:17]([cH:21]4)[O:18][CH2:19][CH2:20]5)[O:13][CH2:14]3)[c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]32)[cH:30][cH:31][cH:32][cH:33][cH:34]1>>[NH:8]1[C:9](=[O:28])[C:10]2([c:11]3[c:12]([cH:15][c:16]4[c:17]([cH:21]3)[O:18][CH2:19][CH2:20]4)[O:13][CH2:14]2)[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]21

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 592633821'-(diphenylmethyl)-6,7-dihydrospiro[benzo[1,2-b:4,5-b']difuran-3,3'-indol]-2'(1'H)-oneHCID 178418361HCID 178418361, compound

Product 1

HCID 592634256,7-dihydrospiro[benzo[1,2-b:4,5-b']difuran-3,3'-indol]-2'(1'H)-one

Sources & evidence

ORD record
ord-fcd541ea37dc42afae7f0227ebdbf6bf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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