8-Quinolinecarboxylic acid → (RS)-1-(2-Benzo[b]thiophen-2-ylmethyl-piperidin-1-yl)-1-quinolin-8-yl-methanone
Reaction equation
[n:17]1[cH:18][cH:19][cH:20][c:21]2[cH:22][cH:23][cH:24][c:25]([C:27](=[O:28])[OH:29])[c:26]12.[s:1]1[c:2]2[c:3]([cH:4][c:5]1[CH2:6][CH:7]1[NH:8][CH2:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][cH:15][cH:16]2>>[s:1]1[c:2]2[c:3]([cH:4][c:5]1[CH2:6][CH:7]1[N:8]([C:27]([c:25]3[cH:24][cH:23][cH:22][c:21]4[cH:20][cH:19][cH:18][n:17][c:26]43)=[O:28])[CH2:9][CH2:10][CH2:11][CH2:12]1)[cH:13][cH:14][cH:15][cH:16]2Participants
3
Sources & evidence
- ORD record
- ord-da45461958f849e58bedc965eb5b1fee
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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