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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 686911Generated: October 26, 2026

1,4-Dioxane → 2-(1-((2-(1-aminoisoquinolin-5-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-ol

https://huagongshe.com/reaction/686911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
ReactantCopper(1+)HCID 104815—
ReactantThiophene-2-carboxylateHCID 5017639—
Reactant1-Amino-5-bromoisoquinolineHCID 33778566—
Reactant2-(1-((9-Methyl-6-morpholino-2-(tributylstannyl)-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-olHCID 59605536—
ReactantHCID 178420554HCID 178420554—
Product2-(1-((2-(1-aminoisoquinolin-5-yl)-9-methyl-6-morpholino-9H-purin-8-yl)methyl)piperidin-4-yl)propan-2-olHCID 59605453—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-9d21340ecddf4f208ae3e92f799e6fbb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)