Sulfuryl chloride → 4-(Tetrahydropyran-4-yloxymethyl)-benzenesulfonyl chloride

HRID 687165Notes

Reaction equation

HRID 687165 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][O:7][CH:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:14][cH:15]1.[CH2:16]([Li:17])[CH2:18][CH2:19][CH3:20].[O:26]1[CH2:27][CH2:28][CH:29]([O:30][c:31]2[cH:32][cH:33][c:34]([S:35]([Cl:36])(=[O:37])=[O:38])[cH:39][cH:40]2)[CH2:41][CH2:42]1.[S:21](=[O:22])(=[O:23])([Cl:24])[Cl:25]>>[c:2]1([S:21](=[O:22])(=[O:23])[Cl:24])[cH:3][cH:4][c:5]([CH2:6][O:7][CH:8]2[CH2:9][CH2:10][O:11][CH2:12][CH2:13]2)[cH:14][cH:15]1

Participants

5

Reactant 4

HCID 24648Sulfuryl chlorideHCID 226656814-[(4-Bromophenyl)methoxy]tetrahydro-2H-pyranHCID 226657534-(Oxan-4-yloxy)benzene-1-sulfonyl chlorideHCID 178418339Butyllithium

Product 1

HCID 226656724-(Tetrahydropyran-4-yloxymethyl)-benzenesulfonyl chloride

Sources & evidence

ORD record
ord-5b9656da7af74e0b9ba93609a093a728
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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