反应详情

Into a 250-mL 3-necked round-bottom flask, was placed malononitrile (20.4 g, 309.09 mmol, 1.00 equiv) at room temperature. To the resulting mixture was then added 1,1,1-triethoxyethane (50 g, 308.64 mmol, 1.00 equiv), in portions at room temperature. To the resulting mixture was then added acetic anhydride (72 g, 705.88 mmol, 2.28 equiv), in portions at room temperature. The resulting solution was heated to reflux for 3 hr. The resulting mixture was concentrated under vacuum, then cooled with a water/ice bath. The solids were collected by filtration to yield 2-(1-ethoxyethylidene)malononitrile as a white solid.

1. customInto a 250-mL 3-necked round-bottom flask, was placed
2. customat room temperature
3. customat room temperature
4. customat room temperature
5. temperatureThe resulting solution was heated
6. temperatureto reflux for 3 hr
7. concentrationThe resulting mixture was concentrated under vacuum
8. temperaturecooled with a water/ice bath
9. filtrationThe solids were collected by filtration